Bifidobacterium infantis 35624, commonly referred to as B. infantis 35624, is a strain of probiotic that is garnering attention for its potential health benefits. As you explore the world of probiotics for gut health, this particular strain stands out for its ability to modulate the gut microbiota, which can be beneficial in improving digestion and may have positive effects on overall health. It’s important for you to understand not only the potential benefits but also how to use it appropriately to ensure you receive the intended effects without adverse side effects.
The interest in B. infantis 35624 is underlined by its unique properties in reducing intestinal inflammation, a feature that may play a role in treating various gastrointestinal conditions. Research suggests that consumption of this probiotic can influence the immune response, promoting the development of tolerogenic dendritic cells and regulatory T cells. These effects could be particularly beneficial for you if you’re dealing with an uncontrolled immune response, such as those seen in certain allergic conditions like asthma.
With these potential health benefits, B. infantis 35624 is becoming more readily available through supplements and various food products. As you consider incorporating this probiotic into your wellness routine, it’s necessary to pay attention to recommended dosages, possible interactions with other medications, and specific storage instructions to maintain its viability. Remember, while B. infantis 35624 could offer health advantages, it’s best to consult a healthcare professional before making it a part of your healthcare regimen.
Taxonomy and Classification
Bifidobacterium infantis 35624, often simply referred to as B. infantis 35624, belongs to a group of bacteria within the genus Bifidobacterium. This genus is a key member of the Actinobacteria phylum, which includes bacteria known for their Gram-positive cell wall structure and high GC content in their DNA.
When you look at the classification hierarchy, B. infantis 35624 resides under:
- Kingdom: Bacteria
- Phylum: Actinobacteria
- Class: Actinobacteria
- Order: Bifidobacteriales
- Family: Bifidobacteriaceae
- Genus: Bifidobacterium
- Species: Bifidobacterium longum
- Subspecies: Bifidobacterium longum subsp. infantis
As a subspecies, B. infantis is noted for its specialization in the human gut and is commonly isolated from the intestines of infants. What differentiates B. infantis 35624 from other strains is its unique ability to utilize human milk oligosaccharides, which positions it as a beneficial probiotic particularly suited for support in infant nutrition and health.
Your understanding of the taxonomic placement of B. infantis 35624 is crucial, as it enables you to grasp its biological role and potential contributions to health. It’s important to note that taxonomy is subject to revision with advancing research and genetic sequencing technologies.
Mechanism of Action
In addressing Bifidobacterium infantis 35624, it’s crucial to understand how it interacts with the body. This probiotic exerts its beneficial effects primarily through immune system modulation and successful colonization of the gastrointestinal tract.
Immune System Modulation
Your body’s immune response can be fine-tuned by B. infantis 35624. It has the capability to:
- Inhibit secretion of pro-inflammatory cytokines such as interleukin-4 (IL-4) and interleukin-13 (IL-13)
- Enhance the presence and function of tolerogenic dendritic cells
- Increase the proportion of regulatory T cells (Treg cells), which play a key role in suppressing inflammatory responses
Gastrointestinal Tract Colonization
B. infantis 35624 is adept at establishing itself in your gut, which is important for its therapeutic benefits. Here’s what happens:
- Adheres to the intestinal epithelium, creating a stable presence
- Interacts with your gut’s native flora, potentially contributing to a balanced microbial environment
- Metabolizes human milk oligosaccharides when available, which can favorably impact its growth and activity in the infant gut
Bifidobacterium infantis 35624 has been the subject of various clinical trials aimed at determining its efficacy in treating certain gastrointestinal conditions and modulating immune responses.
Irritable Bowel Syndrome Research
Bifidobacterium infantis 35624 (B. infantis 35624) has been evaluated in several double-blind randomized studies focused on patients with Irritable Bowel Syndrome (IBS). It has demonstrated effectiveness in alleviating symptoms such as abdominal pain, bloating, and bowel movement irregularity compared to placebo. The use of Rome IV criteria, a more recent diagnostic guideline for IBS, has been factored into these studies to improve diagnostic accuracy.
Infant Colic Treatment
Early research into B. infantis 35624 for treating infant colic has shown promising results. Its use has been associated with a reduction in the duration and frequency of crying episodes in affected infants. The probiotic appears to help in balancing gut bacteria, which is thought to be a factor in colic.
Other Therapeutic Effects
B. infantis 35624 may have wider applications beyond gastrointestinal health. Studies indicate that this strain can influence immune function by inhibiting the secretion of certain pro-inflammatory cytokines, such as interleukin-4 and interleukin-13, and by promoting the increase of regulatory T cells. These immunomodulatory effects could potentially make B. infantis 35624 beneficial for conditions characterized by inflammation, such as asthma, although further research is needed to fully validate these applications.
Safety and Side Effects
When considering the use of Bifidobacterium infantis 35624, a probiotic supplement, it is important to be mindful of both its safety profile and potential side effects. This probiotic is generally considered safe for consumption by the majority of people. However, as with any supplement, there are potential side effects that you should be aware of.
Common Side Effects:
- Stomach discomfort
These are typically transient and may subside as your body adjusts to the probiotic.
Serious Side Effects:
In rare instances, more serious side effects can occur. You should seek medical attention if you experience:
- Signs of infection (e.g., persistent cough, high fever, chills)
- Allergic reactions (e.g., hives, rash, swelling, trouble breathing)
- If you have underlying health conditions, particularly immune system problems, you should talk to your healthcare provider before taking B. infantis 35624 as there is a small risk of developing systemic infections.
- Always check with your healthcare provider prior to beginning any new supplement, especially if you are pregnant, nursing, or taking other medications.
By being aware of these potential side effects and taking necessary precautions, you can better ensure your safety when using Bifidobacterium infantis 35624.
Manufacturing and Commercialization
When you consider the production and distribution of Bifidobacterium infantis 35624, it’s important to recognize the careful processes that ensure its quality and efficacy. This probiotic, which is of human origin, has been patented under the name Bifantis™. The manufacturing adheres to stringent standards to maintain the viability and purity of the probiotic strain.
In terms of commercial availability, this particular strain is marketed as Alflorex® in Europe and as Align® in North America. These products have capitalized on the proven health benefits of B. infantis 35624, which have been supported by clinical research, to gain a strong foothold in the dietary supplement market.
Key Points in the Supply Chain:
- Cultivation: The bacteria are cultivated under controlled conditions to ensure a consistent product.
- Harvesting: After reaching the desired growth, the bacteria are harvested.
- Formulation: The probiotic is formulated into a dietary supplement, with careful attention to maintaining its viability.
- Packaging: Specialized packaging is used to protect the probiotic from external factors like moisture and heat.
- Distribution: The finished product is distributed through various channels to reach consumers.
Companies involved in the production of B. infantis 35624 prioritize maintaining the high standards required for probiotics. You can find these products available over the counter, making them a convenient addition to your health regimen.
Frequently Asked Questions
In this section, you’ll find targeted answers to common inquiries regarding the probiotic Bifidobacterium infantis 35624, its potential health benefits, and its use in dietary supplements.
What are the potential health benefits of taking Bifidobacterium 35624 supplements?
Bifidobacterium infantis 35624 has been shown to modulate the immune response, potentially improving gastrointestinal health by enhancing the proportion of regulatory T cells. It may help alleviate symptoms in patients with irritable bowel syndrome (IBS) and regulate inflammatory processes.
Can Bifidobacterium 35624 aid in weight management, and if so, how?
There is limited direct evidence to suggest that Bifidobacterium infantis 35624 aids in weight management. While some probiotics may influence gut microbiota and have an impact on body weight, further research is necessary to validate these effects specifically for Bifidobacterium infantis 35624.
What differentiates Bifidobacterium longum 35624 from Bifidobacterium infantis, and are both effective for digestive health?
Bifidobacterium longum 35624 is a subspecies of Bifidobacterium infantis, specifically selected for its probiotic potential. Both are recognized for their benefits in promoting intestinal health, but Bifidobacterium infantis 35624 has been extensively studied for its effectiveness in managing IBS symptoms and improving gastrointestinal health.
Which commercially available probiotics contain Bifidobacterium infantis 35624 as an active ingredient?
There are several probiotic products on the market that include Bifidobacterium infantis 35624 as an active ingredient. One such example is Align, a supplement designed to support digestive health, which contains this specific strain.
Are there any known side effects associated with the consumption of Bifidobacterium infantis 35624?
The majority of users tolerate Bifidobacterium infantis 35624 well. However, some individuals may experience mild side effects such as bloating or gas, especially when first starting supplementation. As with any supplement, it’s recommended to consult with a healthcare provider before use.
How might Bifidobacterium infantis 35624 help alleviate symptoms of constipation?
Bifidobacterium infantis 35624 may help to improve bowel regularity and alleviate symptoms of constipation due to its ability to balance the gut microbiota and positively affect the gastrointestinal environment, although individual responses can vary.
Johan Theorin is an author, editor, and competitive cyclist. He is the author of most of the content on this website, and he is the site editor. Johan has spent years researching joint health, sports performance and recovery. He is a leading biohacking expert and an experienced physiotherapist.